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【City Media Focus】Ten Years of Coordinated Development in the Beijing-Tianjin-Hebei Region, Wuqing, the Leading Biotechnology Private Enterprise, Has Risen!

2024 marks the "10th anniversary" of the coordinated development of Beijing Tianjin Hebei region. Over the past decade, the three regions have made significant progress and achievements in various fields such as science and technology innovation, cultural tourism, government services, and healthcare, creating practical and convenient conditions for the people of the three regions and providing caring services.


【City Media Focus】Ten Years of Coordinated Development in the Beijing-Tianjin-Hebei Region, Wuqing, the Leading Biotechnology Private Enterprise, Has Risen!(图1)

Tianjin Novogene


Over the past decade, on the report card of the coordinated development of Beijing Tianjin Hebei region, there is a high-tech enterprise called Tianjin Novogene Biotechnology Co., Ltd. (hereinafter referred to as "Novogene"), which specializes in biotechnology services and genetic testing. The enterprise has always been committed to providing services such as gene sequencing, mass spectrometry analysis, bioinformatics technology support, life science tools, and genetic testing, accelerating the cultivation and development of new quality productivity, and becoming a leading private enterprise in the biotechnology field.


Rooted in the policies of the Beijing Tianjin Hebei region, leading the development of biotechnology


Our Wuqing company currently has three main businesses: biotechnology services, clinical testing, and life science tools. In addition, we also have reagent kits and instruments to assist in precision treatment, "said Cai Jing, Executive Vice General Manager of Novogene. She participated in the construction and development of Wuqing Company, and in the past decade, witnessed the increasing popularity and widespread application of biological gene sequencing and detection technology.

Previously, as an emerging technology field, we mainly focused on universities and research institutes, and had contact with many experts and professors to collaborate on their research topics or provide solutions such as gene sequencing and bioinformatics analysis, "said Cai Jing.

Nowadays, with the increasingly widespread application of gene sequencing technology, our business types are also constantly expanding, "said Cai Jing." Currently, our cooperative clients also include clinical doctors and breeding based enterprises. Since 2015, genetic testing has been widely known. Gradually, based on the precise and rapid characteristics of genetic testing technology, people are increasingly considering genetic testing or molecular breeding methods when facing diseases such as tumors, genetic diseases, infections, and breeding such as seed cultivation and screening, greatly improving efficiency.


【City Media Focus】Ten Years of Coordinated Development in the Beijing-Tianjin-Hebei Region, Wuqing, the Leading Biotechnology Private Enterprise, Has Risen!(图2)

Tianjin Novogene Laboratory


In the past decade, genetic testing technology has undergone a market development process from chaotic expansion to orderly development, and this emerging biotechnology is gradually moving towards positive and sustainable development. In September 2024, Tianjin officially issued the "Implementation Plan for Accelerating the Innovation of Synthetic Biology and Promoting the High quality Development of the Biomanufacturing Industry in Tianjin", proposing to form several innovative achievements in the field of synthetic biology with international influence by 2026, and for the first time in the policy, to establish a legal service mechanism for intellectual property protection in this field nationwide.

At the same time, in September of this year, under the joint guidance of the Municipal Science and Technology Bureau, Municipal Health Commission, Municipal Drug Administration, Municipal Medical Insurance Bureau, and Municipal Industry and Information Technology Bureau, the Tianjin Biomedical Industry Alliance was officially established by 95 alliance member units, covering key enterprises, research institutes, medical institutions, and financial institutions in the field of biomedicine in our city. The establishment of the alliance will continuously integrate Tianjin's biopharmaceutical resources and enhance the technological innovation capability of the biopharmaceutical industry.

Currently, based on its location advantage, Tianjin University Frontier Technology Research Institute (Wuqing) has established a communication channel with Novogene and is carrying out the National Key Research and Development Program for Synthetic Biology. The two sides are cooperating in the fields of research and development, genetic testing verification, and DNA storage, and the project is currently progressing very smoothly, "said Cai Jing.


Responding to the national strategy of focusing on genetic testing technology


In response to the national strategy of coordinated development of the Beijing Tianjin Hebei region, since the establishment of the experimental base in Wuqing in 2014, Novogene has assisted scientific innovation in various fields such as species research, disease and cancer mechanism research, translational medicine research, environmental protection, etc., and expanded the clinical application of gene technology in human health, empowering precision medicine and using gene technology to safeguard life and health.

At Wuqing Company, in addition to the main person in charge from the Beijing company, the company has gradually grown from a small team of 20-30 people to over 1000 people. They come from major universities across the country, with more than half of them holding master's degrees or above, engaged in production and research and development related work. At the same time, Novogene develops suitable professional skills and general quality training for talents, including basic skills and comprehensive quality training such as operational skills and platform usage, and builds a talent gradient training system.

Ma Ce is from Shijiazhuang, Hebei. After graduating with a master's degree, he joined Novogene and has been working in the field of biotechnology for nearly 10 years. He has settled down in Wuqing. In the past three years, in response to the national strategy of revitalizing the seed industry, as the head of the breeding product department of Novogene, he has led a team to focus on breeding and screening of crops and animal husbandry. Starting from the national strategy and focusing on the core process of breeding, we will continue to do relevant work for the revitalization of the national seed industry, "said Ma Ce.

To determine whether a seed is of the highest quality, it needs to be artificially cultivated and screened, "Ma Ce said." The traditional breeding process requires a lot of manpower and material resources, and can take up to 5-6 years at the fastest. Molecular breeding, on the other hand, reduces manpower and improves efficiency, increasing time by two-thirds and reducing costs by 60%.

On September 9, 2024, the latest research article on soybean breeding and improvement project jointly conducted by Novogene and Hebei Agricultural University was published in an international journal, revealing studies related to agronomic traits such as soybean yield and seed quality.


【City Media Focus】Ten Years of Coordinated Development in the Beijing-Tianjin-Hebei Region, Wuqing, the Leading Biotechnology Private Enterprise, Has Risen!(图3)

Tianjin Novogene Sequencing Laboratory


How to select a high-quality seed? Ma Ce introduced that "the key to breeding is selection, and the key to selection is to improve the accuracy of seed selection." To this end, he and his team members used whole genome selection technology to effectively improve the accuracy and genetic progress of breeding, shorten generation intervals, and reduce the cost of artificial breeding.

For example, cultivating high-quality pigs is like giving pigs a "beauty pageant", using genetic testing methods to quickly identify healthy and high-quality genes, and select pig babies who grow faster, stronger, and of higher quality. However, in actual research, he admitted that there is still a significant gap between the research on whole genome selection technology in pig breeding and that of foreign countries. In the "13th Five Year Plan" and "14th Five Year Plan" for agricultural animal breeding, whole genome selection technology has been listed as one of the key breeding technologies for development and research in China.

The core of the revitalization of the seed industry is to accelerate the improvement of breeding level. In order to achieve national self-reliance and self-improvement in the seed industry, he and his team members continue to research and develop soybean, corn, pig, and beef cattle breeding. They provide reliable molecular breeding data and analysis for relevant universities, research institutes, and enterprises, clarify research directions, and help researchers avoid detours and accelerate the improvement of breeding technology.


Intelligent production lines support the innovative development of biotechnology


To achieve digital and automated development, Novogene continuously promotes the establishment of industry standards and realizes true intelligent transformation. Since 2020, based on the integration of 66 precision equipment into the intelligent delivery platform, Novogene has achieved full process intelligent operations from sample extraction, detection, library construction, library inspection, and bioinformatics analysis.

There is no manual intervention in the sample detection and analysis process, maximizing the pollution-free and accurate analysis and reliability of the detection process. The sample processing efficiency of the intelligent delivery platform has also been greatly improved, running efficiently 24 hours a day, fully ensuring the cycle of large-scale projects. In addition, the entire production process can be traced, "said Cai Jing.

At present, Novogene has established 10 laboratories in Beijing, Tianjin, Guangzhou, Shanghai, the United States, the United Kingdom, Germany, Singapore, and Japan in accordance with international, domestic, and provincial standards, providing global scientists with services such as gene sequencing, mass spectrometry analysis, and bioinformatics technology support, and has obtained certifications from multiple authoritative institutions at home and abroad.


【City Media Focus】Ten Years of Coordinated Development in the Beijing-Tianjin-Hebei Region, Wuqing, the Leading Biotechnology Private Enterprise, Has Risen!(图4)

Falcon, an intelligent delivery platform


The biopharmaceutical industry is an advantageous industry in Wuqing District. Wuqing District is committed to building a "3+3+4" industrial system, which includes cultivating three billion level industrial clusters of intelligent technology, biomedicine, and high-end fashion consumption, strengthening three advantageous industries of equipment manufacturing, automobiles and core components, and new materials, and laying out four future industries of future intelligence, DNA storage, new energy storage, and cutting-edge new materials. It closely focuses on implementing the major national strategy of coordinated development in the Beijing Tianjin Hebei region, adheres to the dual high leadership of "intelligent technology and biomedicine", accelerates the supplementation of short board industries, the extension of advantageous industries, and the construction of emerging industries, and comprehensively enhances the continuity and competitiveness of industrial development.

At present, there are more than 200 biopharmaceutical industry chain enterprises in Wuqing District, among which leading companies in the biopharmaceutical industry such as Novogene and GensKey have been listed as the fifth batch of specialized, refined, and new "little giant" enterprises in Wuqing District.

We will continue to increase our efforts in nurturing and strengthening collaborative cooperation with relevant departments. Through precise policy support, innovation capability enhancement, coordinated development of the industrial chain, talent introduction and training, and optimization of the service environment, we will support enterprises in implementing digital empowerment actions, creating new driving forces, tackling new technologies, and developing new products. We will fully support the development of the biopharmaceutical industry, steadily strengthen the group of "small giants" in the field of college, technology, and innovation, create more influential "hidden champions" and "single champions", and promote more small and medium-sized enterprises to move towards "specialized, refined, unique, and new small giants", "said Sun Li, Director of the Industrial Policy Department of Wuqing District Bureau of Industry and Information Technology.

Novogene is a representative of high-tech enterprises in the field of biomedicine in Tianjin. In recent years, the Municipal Science and Technology Bureau has attached great importance to Novogene's innovative development and supported the enterprise in carrying out gene testing research and development platform construction, reagent kit product development, etc. "Zhang Yuewei, Director of the Biomedical Department of the Municipal Science and Technology Bureau, said when talking about the enterprise that as the leading department of the Tianjin Biomedical Industry Development Work Team, the Municipal Science and Technology Bureau insists on asking for needs and planning from enterprises, continuously strengthening top-level design and enterprise services. Recently, the Municipal Science and Technology Bureau is studying and formulating several opinions to support the innovation and development of biopharmaceuticals throughout the entire chain, covering various aspects such as innovation source, registration review, clinical application, market access, etc. It is hoped to create a full chain and full life cycle support service system for the biopharmaceutical industry and create a good ecology for the development of the biopharmaceutical industry in Tianjin.

Source:TJYun

Release Time:2024-12-11 17:40:00